Bro, are you seriously against male contraception? The pill has failure rates of 9 friggin' percent of typical use. 99% for typical use would be amazing.

[–] unexposedhazard@discuss.tchncs.de 1 points 2 days ago

If you combine it with the 99.9% (made up number) of condoms then you are pretty damn safe tho.

[–] BagOfHeavyStones@lemm.ee 1 points 2 days ago

Or just the wrong hole at the wrong time.

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[–] HelixDab2@lemm.ee 1 points 1 day ago

I'm skeptical. Anything targeting signalling pathways seems likely to have consequences that aren't apparent from animal trials. I remember a few years back that MENT (trestolone, 7α-methyl-19-nortestosterone) was being investigated for use as male contraceptive, and one of the biggest issues I recall was that it caused really wild mood swings in a number of men. Admittedly, MENT is hormonal, but I don't think that issues it caused were anticipated; I think the profile looked much more promising than it ended up being.

[–] Aliveelectricwire@hexbear.net 0 points 1 day ago

I was already considering hitting up my fwb who has a breeding fetish tbh. Now I'm def gonna quit doomscrolling and [REDACTED]

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