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To be fair, dosing babies with anesthesia is way more difficult, and there’s zero record of whether they have any drug allergies or intolerances
Nowadays, you can test for anesthetic drug resistances with DNA site testing, (as in, a blood test), though of course, this does not mean that it is always used, for various reasons.
A personal anecdote:
I've had one done after I had bad side-effects to ADHD medication I had tried, and I haven't had any bad effects in the medications I've tried since. (besides drowsiness)
Edit: I want to say, I'm not saying that getting the dosage right is not incredibly difficult, I just wanted to mention that we can detect drug allergies without putting them under, (so to speak).
That’s good to know! I just swelled up for a week because my new dentist used a different kind of local anesthetic, so it was close to the front of my mind. That would have helped a lot