Here's an edited list of what I exclude from my full system backup on my debian machine:
<Exclude>
<Item>/.Trash-*/</Item>
<Item>/.recycle/</Item>
<Item>/*.pyc</Item>
<Item>/var/cache/apt/archives</Item>
<Item>/tmp/</Item>
<Item>/proc/</Item>
<Item>/dev/</Item>
<Item>/sys/</Item>
<Item>/run/</Item>
<Item>*/RecentDocuments/</Item>
<Item>*/.cache/</Item>
<Item>*/Trash/</Item>
<Item>*/recentfolders/</Item>
<Item>*/pictureCache/</Item>
<Item>*/Crash Reports/</Item>
<Item>*/GLCache/</Item>
<Item>*/cache/</Item>
<Item>*/tmp/</Item>
<Item>/var/log/</Item>
<Item>*/.xsession-errors</Item>
<Item>*.swp</Item>
<Item>/var/lib/samba/private/msg.sock</Item>
<Item>/home/jt/.local/share/baloo/</Item>
<Item>/home/jt/.mozilla/firefox/*/sessionstore-backups/</Item>
<Item>/home/jt/.mozilla/firefox/*/crashes/</Item>
<Item>/home/jt/.mozilla/firefox/*/datareporting/</Item>
<Item>/home/jt/.local/share/Steam</Item>
<Item>*/.thumbnails/</Item>
<Item>*/.cache/</Item>
<Item>*/lost+found/</Item>
<Item>/mnt/</Item>
<Item>/*.bash_history</Item>
<Item>/opt/firefox</Item>
<Item>/home/jt/.local/share/klipper/history*.lst</Item>
<Item>*/steam.pipe</Item>
<Item>*/recently-used.xbel</Item>
<Item>/home/jt/.mozilla/firefox/*/storage/</Item>
<Item>/home/jt/.local/share/kpeoplevcard</Item>
</Exclude>