• A bug in the code controlling the Therac-25 radiation therapy machine was directly responsible for at least five patient deaths in the 1980s when it administered excessive quantities of beta radiation.
• Radiation therapy planning software RTP/2 created by Multidata Systems International could incorrectly double the dosage of radiation depending on how the technician entered data into the machine. At least eight patients died, while another 20 received overdoses likely to cause significant health problems (November 2000).
• A Medtronic heart device was found vulnerable to remote attacks (2008-03).

https://en.wikipedia.org/wiki/List_of_software_bugs#Tracking_years