I learned about Linus Pauling's ideas on Vitamin C supplementation. Pretty interesting stuff, especially wrt heart disease. I'm paraphrasing but if I remember correctly he theorized that our appendix used to produce vitamin C and that it somehow mutated away from that, and the lack of the vital nutrient causes heart disease problems with humans and all the great apes. Apparently we all get heart disease like cats have bad kidneys. He thought huge doses of vitamin C were the answer.

[–] volvoxvsmarla@lemm.ee 3 points 4 days ago (1 children)

Yes, he is usually (and anecdotally) used in every introduction to works that cover vitamins and supplementation 😅 but unfortunately his ideas weren't really backed by science. If you eat more vitamin c than you can absorb, you just pee it out. We actually did that in university (control group, breakfast group, breakfast + 1g of vitamin c group, testing the pee and I think capillary blood). Now, I think there are some findings with intravenous vitamin c acting like an oxidizing agent and killing cancer (?) cells, but macrodosing orally just doesn't give you any effect.

Also, fun fact, your RDA can be met by eating one frozen pizza because vitamin c is used as a food additive everywhere.

[–] shneancy@lemmy.world 1 points 4 days ago

macrodosing vitamin c gives my awful stomach cramps :(