this post was submitted on 27 Sep 2025
801 points (99.9% liked)

Uplifting News

16709 readers
873 users here now

Welcome to /c/UpliftingNews (rules), a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity and rage (e.g. schadenfreude) often found in today's news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news—in text form or otherwise—that gives hope, fosters empathy, and strengthens the belief in humanity's capacity for good, from a quality outlet that does not publish bad copies of copies of copies.

Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else's big ray of hope. Be part of the positivity revolution; share, uplift, inspire!

founded 2 years ago
MODERATORS
top 50 comments
sorted by: hot top controversial new old
[–] SpiceDealer@lemmy.dbzer0.com 13 points 3 hours ago (1 children)

Pastors: NO! How will I condemn the gays now?!

Capitalism: That's great but what's the profit margin?

[–] JargonWagon@lemmy.world 5 points 1 hour ago* (last edited 1 hour ago)

Fascists: That drug causes autism, use this one instead (that just so happens to also profit us)

[–] qualia@lemmy.world 6 points 3 hours ago

Just to clarify the potentially confusing title. This drug came out three months ago in the US, is a version of PrEP (pre-exposure prophylaxis) that only needs to be taken every six months, and is free with most insurances if you're in an at-risk demo.

[–] Deflated0ne@lemmy.world 13 points 6 hours ago (2 children)

$80 in the US. Because our president is a buffoon

banned in the us. because the president and health secretary is a bag of dicks.

[–] qualia@lemmy.world 7 points 5 hours ago (2 children)

Free with many insurances though! It may take a little longer to get a "Prior Authorization," but as long as you say you're in an at-risk group for HIV (Google these) it will eventually get approved.

The rationale is that since treating HIV+/AIDS is so astronomically more expensive than merely paying for this once every 6 months PrEP, that insurance actuaries determine the latter to be way more in the insurance company's interest.

This is good since it doesn't require the insurance companies to be ethical, just cheap. But a win-win is still a win-win, so I say take it where you can get em. {Former pharmacist here, feel free to reach out and ask how to get non-addictive drugs covered} 🪿

[–] InquisitiveYum5003@lemmy.dbzer0.com 2 points 3 hours ago (1 children)

Hi Qualia, my brother is medically obese and uninsured. Does he have any chance of getting some sort of weight loss drug for free or low-cost? He has sleep/wake cycle problems too.

[–] qualia@lemmy.world 1 points 1 hour ago

slid into yer DMs

[–] Rekorse@sh.itjust.works 2 points 4 hours ago* (last edited 4 hours ago)

I somehow read your post as "Free with insurgencies". Not sure what thats about.

[–] selkiesidhe@sh.itjust.works 29 points 21 hours ago (3 children)

Sounds like a good thing therefore the brainworm in charge of health here in the states will surely get it banned. Or at least made to cost several thousand percent more than it costs to make.

[–] aeternum@lemmy.blahaj.zone 8 points 12 hours ago* (last edited 12 hours ago)

$40 a year somewhere else? That'll be $40K a year in america.

[–] Cassanderer@thelemmy.club 1 points 12 hours ago (1 children)

Not quite brainworm's fault we are getting extorted for drugs.

[–] BarneyPiccolo@lemmy.today 4 points 4 hours ago

Maybe not, but you can always count on MAGA to exploit a broken policy rather than fix it.

[–] IphtashuFitz@lemmy.world 10 points 21 hours ago (1 children)

Thank goodness the west coast states have created their own health consortium and a bunch of east coast states have followed suit. I live in one of those east coast states, and just got a covid booster no questions asked. It is also covered 100% by my insurance.

[–] sol6_vi@lemmy.makearmy.io 1 points 4 hours ago

So do I and I did the same and it was so easy. I felt hella privileged sitting in that chair this year.

[–] tehredmage@lemmy.dbzer0.com 10 points 21 hours ago (3 children)

"Preventative drug"? Is this what we're calling vaccines now?

[–] SaveTheTuaHawk@lemmy.ca 8 points 6 hours ago (1 children)

HIV infects the immune cells, which is why attempts at vaccines failed.

[–] qualia@lemmy.world 3 points 5 hours ago (1 children)

Yeah HIV doesn't use traditional warfare: it bombs hospitals. 😔

[–] Dremor@lemmy.world 5 points 4 hours ago

That's standard warfare to some these days.

[–] CheesyFox@lemmy.sdf.org 11 points 13 hours ago (2 children)

vaccine is a scientific term, meaning a weaker (or, rather, as weak as scientifically possible) version of the same virus / bacteria, so that immune system could learn to fight it without dying in the process.

This is not a vaccine, as has an active substance, that chemically interacts either with our body, HIV's shell, or both

[–] olafurp@lemmy.world 2 points 3 hours ago* (last edited 3 hours ago) (1 children)

There are more ways, weak virus, dead virus, modified virus, payload swap virus and an mRNA blast.

Would love to see this HIV vac get more development and become permanent and a part of infant vaccine routine until it just fucking dies.

[–] CheesyFox@lemmy.sdf.org 2 points 3 hours ago

of course there are. I was axcited to hear about Vectors when they were developed. It's nice to see scientists come up with something new

[–] Dremor@lemmy.world 1 points 4 hours ago (1 children)

MRNA vaccine works differently if I remember well. Basically instead of injecting the weaker virus itself, they trick the body to produces non-active parts of that pathogens in order to train the body.

[–] CheesyFox@lemmy.sdf.org 1 points 4 hours ago (1 children)

wow, cool, good to know something like that exists. What are we vaccinating against with MRNA?

[–] Dremor@lemmy.world 3 points 4 hours ago (1 children)

Covid. Like 80% of the vaccine where mRNA based.

[–] CheesyFox@lemmy.sdf.org 1 points 2 hours ago
[–] stoly@lemmy.world 12 points 17 hours ago (1 children)

There are No vaccines for HIV. This is a drug that if taken continually will prevent the virus from taking hold.

[–] Tabula_stercore@lemmy.world 1 points 12 hours ago (2 children)

It is an interesting what makes the distinction.

The core principle of vaccination is training the immune system with a substance so that a disease can be defeated later on.

Nothing says that a vaccine needs to be an injection. There are injection vaccines that need multiple doses before the immune system reaches a certain level.

So why would a pill that trains your immune system not be a vaccine?

[–] SaveTheTuaHawk@lemmy.ca 3 points 6 hours ago (1 children)

It's not a vaccine. It does not trigger an immune response. Science says vaccines cannot be pills, they either need to be intramuscular or inhaled aerosol. This is because they are proteins, which get digested through the stomach and gut.

[–] Dremor@lemmy.world 1 points 4 hours ago* (last edited 4 hours ago)

Some vaccine are oral based (but as a liquid, not as pill). We don't use them in the West as we have robust viccine that are injection based. But those vaccine requires a way more robust supply chain than many third world countries has, so oral vaccine, while not as effective as injection based vaccine, are used there.
Problem with oral vaccine is that most pathogens are killed by the digestive system so the only one that could be made as a pill would be those who already are acclimated to such a harsh environment (so gut microbiology).
There are very few digestive disease that would allow for such vaccine vector to be developed, the only one that could these last few decade would be Ebola. But for such a deadly disease (90% mortality if I remember well), the medical community would prioritize the most effective way, which would be injection.

[–] CXORA@aussie.zone 6 points 12 hours ago

I guess a pill could be a vaccine, but this drug is neither a vaccine nor a pill, so I have no clue why youre bringing this up.

[–] Confused_Emus@lemmy.dbzer0.com 45 points 1 day ago (1 children)

Generic versions of a groundbreaking injectable HIV-prevention drug should be available for $40 a year in more than 100 countries from 2027, Unitaid and the Gates Foundation said Wednesday.

Marketed under the brand name Yeztugo by California-based Gilead Sciences, lenacapavir currently costs around $28,000 a year in the United States.

FUCK GILEAD

[–] jumping_redditor@sh.itjust.works 2 points 13 hours ago

clearly they should have tried a smaller time frame to get a more reasonable price

[–] MangioneDontMiss@feddit.nl 89 points 1 day ago (9 children)

40 dollars in low income countries. 28,000 dollars in the united states. The drug is made in the united states.

WTF.

[–] sga@piefed.social 14 points 23 hours ago (3 children)

speaking as a indian - the reason that this is possible because we kinda ignore medical patents and formulations. (using kinda because i do not know the exact wording in law and the cooldown period).

It should also tell you about the cost of ingredients and manufacturing vs the costs you pay for "rnd for big companies" (who often build upon work done by universities which often are run by public fundiing)

[–] SaveTheTuaHawk@lemmy.ca 4 points 6 hours ago

15 years on patent drugs.

[–] SaveTheTuaHawk@lemmy.ca 3 points 6 hours ago

Pharmaceutical companies used to do basic research until the 90s. At this point, they are just banks who buy biotechs spun out from NIH research.

Now that NIH is gone, the industry will atrophy within a decade. There will be no new drugs.

[–] Alcoholicorn@mander.xyz 4 points 12 hours ago

Those companies spend more on advertising than RND

[–] SaveTheTuaHawk@lemmy.ca 40 points 1 day ago (1 children)

Makes you wonder if Trump has a point.

But thanks to RFK and Trump, there will be no more drugs like this in the future. Gilead did the trials, but 95% of the effort behind this was NIH funded. We can't even guess how many game changing drugs have been cut in 2025.

[–] AA5B@lemmy.world 22 points 1 day ago* (last edited 1 day ago) (5 children)

As always Trump completely misunderstands the situation. Yes there’s a point in how exepnsive drugs are in the us, especially relative to other countries. But whether it’s manufactured in the us has almost nothing to do with it.

The problem is recovering all the development costs from American patients, and more recently just charging what they think the market will bear. We have to fix the complex maze of healthcare and all the levels of profiteering, we have to fix how development costs can be recovered and most of all we need to fix charging what the market will bear. Has everyone already forgotten the outcry over insulin a few years ago. A ceo who should be in jail decided to start charging ten or twenty times the cost, because he could, because us patients are a captive market. Then got away with saying “some of you can use these coupons….”. There’s definitely a point where exploitive business practices have crossed the line and should be considered criminal acts

[–] kbobabob@lemmy.dbzer0.com 2 points 3 hours ago

A hell of a lot of that is funded by tax payers. They don't need to recoup money, they need to give the tax payers what they already paid for.

[–] SaveTheTuaHawk@lemmy.ca 3 points 6 hours ago (1 children)

Drug development in trials costs $120-200M. Upon approval, Pharma expects $15B +.

They have proven they would rather a drug not save lives than offer lower profits.

if a product can be sold at 10 times the profit to one fifth the people only an idiot would not rase prices ten fold

load more comments (3 replies)
load more comments (7 replies)
load more comments
view more: next ›