this post was submitted on 08 Nov 2024
436 points (99.8% liked)

News

23397 readers
3614 users here now

Welcome to the News community!

Rules:

1. Be civil


Attack the argument, not the person. No racism/sexism/bigotry. Good faith argumentation only. This includes accusing another user of being a bot or paid actor. Trolling is uncivil and is grounds for removal and/or a community ban. Do not respond to rule-breaking content; report it and move on.


2. All posts should contain a source (url) that is as reliable and unbiased as possible and must only contain one link.


Obvious right or left wing sources will be removed at the mods discretion. We have an actively updated blocklist, which you can see here: https://lemmy.world/post/2246130 if you feel like any website is missing, contact the mods. Supporting links can be added in comments or posted seperately but not to the post body.


3. No bots, spam or self-promotion.


Only approved bots, which follow the guidelines for bots set by the instance, are allowed.


4. Post titles should be the same as the article used as source.


Posts which titles don’t match the source won’t be removed, but the autoMod will notify you, and if your title misrepresents the original article, the post will be deleted. If the site changed their headline, the bot might still contact you, just ignore it, we won’t delete your post.


5. Only recent news is allowed.


Posts must be news from the most recent 30 days.


6. All posts must be news articles.


No opinion pieces, Listicles, editorials or celebrity gossip is allowed. All posts will be judged on a case-by-case basis.


7. No duplicate posts.


If a source you used was already posted by someone else, the autoMod will leave a message. Please remove your post if the autoMod is correct. If the post that matches your post is very old, we refer you to rule 5.


8. Misinformation is prohibited.


Misinformation / propaganda is strictly prohibited. Any comment or post containing or linking to misinformation will be removed. If you feel that your post has been removed in error, credible sources must be provided.


9. No link shorteners.


The auto mod will contact you if a link shortener is detected, please delete your post if they are right.


10. Don't copy entire article in your post body


For copyright reasons, you are not allowed to copy an entire article into your post body. This is an instance wide rule, that is strictly enforced in this community.

founded 1 year ago
MODERATORS
 

Summary

The FDA has proposed removing oral phenylephrine, a common ingredient in over-the-counter cold medicines like NyQuil and Sudafed, due to evidence that it is ineffective as a nasal decongestant.

The proposal follows a unanimous vote by FDA advisers last year, and recent studies showing less than 1% of the drug is absorbed into the bloodstream when taken orally.

The public comment period ends on May 7, after which the FDA may finalize the ban.

top 50 comments
sorted by: hot top controversial new old
[–] HEXN3T@lemmy.blahaj.zone 1 points 2 days ago

Late reply, but I'm currently sick, and saw this as an opportunity.

I have never had much success with OTC cold medicines. The best I've seen is Alka Seltzer Plus and Mucinex, but I felt these always underperformed significantly. With other commenters offering advice, and the internet being vast, I did some research.

I ended up taking Sudafed (bought today) and Zyrtec (always have on hand). I also took Excedrin for pain relief (last dose I had).

I'm still sneezing occasionally, and my nose is slightly tingly, but I feel obviously better than before--much better success than I've seen with other OTC drugs.

I don't have ibuprofen, but I suggest that over Excedrin. Excedrin contains acetaminophin (and aspirin--important!), as well as caffeine. Essentially, I'd recommend doing the following, as directed on packaging:

Pseudoephedrine (DANGEROUS MAOI INTERRACTION--Non-Rx, non-OTC, works well for congestion)

Antihistamine (Zyrtec, Allegra--Benadryl if you feel like seeing the hat man)

Ibuprofin (NSAID--do NOT take with alcohol or other NSAIDs--reads more effective as an NSAID than aspirin and acetaminophen. Most effective NSAID of the three)

Caffeine (Tea is probably better than coffee--helps with pain slightly, but especially drowsiness, and therefore depends on time of day)

For something more unique, cannabis products are certain to help without all too much risk. I experience neck pain when I'm sick, so lightly smoking helped. CBD oil works super well for specific spots, and is probably better than THC for most people. This is a sure-fire way to help with pain and insomnia, but I hope you aren't that sick.

Finally, another unique suggestion, and one you'll only see from me. Proceed with reasonable caution and do your research, though. Red kratom strains, or green if you prefer something a little easier on the system--faster onset, too. Recent "gas station heroin" headlines are fearmongering and utter bollocks, in a surprise to nobody. Thanks, Nixon. Kratom helps considerably with pain/insomnia, but it's somewhat risky to use kratom with NSAIDs and antihistamines. Don't see issues with pseudoephedrine. I sincerely doubt a 4g toss-and-wash is going to do more harm than good, but please measure by weight, and not volume. Do the minimum effective dose. Yet again, do not drink with alcohol--it's horrible on the liver. Just don't drink in general, to be honest. All in all, I'd honestly suggest picking between either your NSAID of choice, or kratom--not both. If you're really being kept awake, or you're really in pain, then kratom is likely the better option over your Excedrins or Tylenols. Sorry this section's long--it's important that it's detailed, for obvious reasons.

Quite a lot at once--balance doses responsibly, experiment, see what works, and stick with that when you fall ill. It's a lot of information, but safety isn't something to compromise with. I hope I've been helpful. That's all, folks.

[–] iAmTheTot@sh.itjust.works 118 points 2 weeks ago (1 children)

Yet the homeopathy pills can still be on the shelves right next to real medicine.

[–] PaupersSerenade@sh.itjust.works 42 points 2 weeks ago (4 children)

From my understanding they don’t need to be FDA approved. At that point blame the store, not the FDA. I’m just glad they’re getting this done before they’re purged by the next administration

[–] TheLowestStone@lemmy.world 27 points 2 weeks ago

I'll blame both.

[–] iAmTheTot@sh.itjust.works 16 points 2 weeks ago

Oh I'll blame both, thank you very much. It's well within certain governed agencies authority to say "you cannot sell that next to real medicine".

load more comments (1 replies)
[–] Mercuri@lemmy.world 64 points 2 weeks ago* (last edited 2 weeks ago) (12 children)

Good. Now do something about homeopathy. I'm so sick of having to explain to people that homeopathy is not medicine in any shape or form. It's not even a home remedy. And it sits right next to actual medicine so people might accidentally buy it unwittingly.

[–] CmdrShepard42@lemm.ee 14 points 2 weeks ago (1 children)

This was so infuriating during covid as it was hard to find children's cold medicine already and half the time you'd see a couple bottles of "Children's cold and flu" on the shelf, buy it, and get home before you notice "homeopathic" written in 3pt font along the bottom of the bottle. Shit's completely useless.

[–] Mercuri@lemmy.world 8 points 2 weeks ago

I've gotten into the habit of checking active ingredients after almost accidentally buying something homeopathic that was immediately adjacent the thing I actually meant to grab.

[–] ipkpjersi@lemmy.ml 6 points 2 weeks ago (1 children)

I'm sure the Trump Administration will get right on banning homeopathy, or even just labelling it properly. lol

load more comments (1 replies)
[–] roguetrick@lemmy.world 6 points 2 weeks ago

The problem is, unlike homeopathy, this drug was ineffective for what it was approved for while actually causing side effects. At least the water doesn't do anything.

load more comments (9 replies)
[–] originalucifer@moist.catsweat.com 54 points 2 weeks ago (2 children)

funny considering they caused the use of this garbage because we cant have real ephedrine cuz tweakers.

was anyone under the delusion this shit worked?

[–] Stalinwolf@lemmy.ca 37 points 2 weeks ago* (last edited 2 weeks ago) (9 children)

My former boss (Canada) kept a bag of ephedrine bottles in our produce cooler. Dude was twitchy as fuck. Very bird/dinosaur-like.

He would take several per day and chase them with coffee and energy shots. Then he would complain intermittently about vomiting blood due to his ulcers.

[–] Track_Shovel@slrpnk.net 22 points 2 weeks ago

He's probably dead now. Ulcers are no laughing matter.

load more comments (8 replies)
[–] Hideakikarate@sh.itjust.works 25 points 2 weeks ago (2 children)

Who says you can't? I can walk up to the pharmacy counter and get some with ID. It's usually a helluva lot cheaper than the phenylephrine stuff, too.

duude i totally forgot they hid it behind the counter.

i grew up being able to buy full bottles of almost pure ephedrine billed as a 'stay awake' thing for truckers and the like. like no-doze

[–] iopq@lemmy.world 4 points 2 weeks ago

Yeah, you have to know about it to ask for it. Most people would buy the useless shit

[–] jballs@sh.itjust.works 37 points 2 weeks ago (1 children)

I remember like a year or two ago when they officially announced these products are LESS effective than a placebo. How the hell is it taking so long to get them off the shelves?

[–] LifeInMultipleChoice@lemmy.world 13 points 2 weeks ago* (last edited 2 weeks ago)

I assume they submitted the results and stated they need to be removed, then reviewed the supreme courts measure that stated they only have power to make measures if Congress grants them privilege to do so (precidence, set in Julyish of 2022 with the EPA) making the specialized divisions of government created by Congress illegitimate unless Congress votes on the measure afterwards, making them just superficial recommendations for Congress to wait and see what their lobbyists think is okay.

Aka will drug companies pay enough to keep us lying to the public, vs maybe we will go by the recorded data.

Exon mobile recorded their data of environmental impacts in what year? And we had battery powered vehicles traveling up to 100 miles before that time. Instead of doing what was best for the future of the people, we chose what was best for profits. Reference article for fun; https://www.corporateknights.com/transportation/half-a-century-ago-one-u-s-senator-fought-to-ban-gas-powered-cars-almost-won

Point being. what power did they have to remove them from the shelves. I assume they are launching these last ditch efforts before Biden leaves, and praying to get some support before they get chiseled away at.

Imagine where we would be if GM/Ford and such started forcing the R&D in 1975 instead of 2005, 2015 or whatever we call it now

[–] roguetrick@lemmy.world 34 points 2 weeks ago

Fucking finally.

[–] Burn_The_Right@lemmy.world 27 points 2 weeks ago (1 children)

These products will mysteriously re-appear after inauguration.

[–] atzanteol@sh.itjust.works 12 points 2 weeks ago

It won't even take that - you can sell products that don't work (airborn, homeopathy, etc.), you just can't claim that it does. So they'll slap the standard "this product is not intended to treat, cure, or prevent any disease" disclaimer on it and people will continue to buy it.

[–] ipkpjersi@lemmy.ml 19 points 2 weeks ago

Something tells me the Trump Administration won't allow this ban to go through.

[–] bitchkat@lemmy.world 19 points 2 weeks ago (1 children)

Is this the shit they started using when they started using the original stuff to make meth?

[–] Verat@sh.itjust.works 15 points 2 weeks ago

By my understanding yes, pseudoephedrine was being used for meth so they put it behind the counter and the name brand "Sudafed" made a PE line that was this, phenylephrine, to stay over the counter.

[–] Corkyskog@sh.itjust.works 19 points 2 weeks ago (1 children)

I have been railing about how this shit doesn't work for what feels like forever.

The entire cold/cough aisle is essentially a scam. Pick up some generic diphenhydramine, APAP, ibuP, and some Pseduophedrine. It will cheap as dirt and do all the things that overpriced shit will do. Anything else that actually helps with a cold/cough is prescription only.

[–] chiliedogg@lemmy.world 9 points 2 weeks ago (1 children)

Pseudoephedrine can't legally be sold in the aisles, and requires you to get out from the pharmacist's counter and provide an ID.

That's why they push the aid that doesn't work. It can be sold at a gas station and after hours.

[–] MIDItheKID@lemmy.world 5 points 2 weeks ago (1 children)

Damn meth heads ruining it for the rest of us.

load more comments (1 replies)
[–] hedgehogging_the_bed@lemmy.world 16 points 2 weeks ago (3 children)

Oooo! Do Guaifenesin next! That also has basically no evidence of effectiveness despite being on the market for ages.

[–] quicklime@lemm.ee 5 points 2 weeks ago

Guaifenesin works very very well for me as an expectorant.

[–] peopleproblems@lemmy.world 5 points 2 weeks ago

That I didn't know. Does that mean that the benefit from it just comes from drinking the insane amount of water it recommends?

[–] Corkyskog@sh.itjust.works 4 points 2 weeks ago

The entire cough/cold aisle is a gigantic scam of combo meds.

[–] atzanteol@sh.itjust.works 12 points 2 weeks ago* (last edited 2 weeks ago)

It won't be pulled from the shelves - it'll just be getting some new fine-print.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

[–] Nottalottapies@aussie.zone 11 points 2 weeks ago (1 children)

About time. Thankfully in Australia we can still get access to the ones containing psuedoephedrine, which works amazingly well.

Can't believe it has taken this long to see the inefficacy of these.

[–] Mercuri@lemmy.world 4 points 2 weeks ago (3 children)

In the US, you can still get the stuff containing pseudoephedrine but you have to go to the pharmacy and ask for it and then show your ID. Out of curiosity, what's the process in Australia?

load more comments (3 replies)
[–] phoenixz@lemmy.ca 9 points 2 weeks ago

No worries, three months from now it'll all be back on the shelves again

[–] grasshopper_mouse@lemmy.world 9 points 2 weeks ago (1 children)

Nobody is taking Nyquil to decongest, they're taking it to pass the fuck out.

load more comments (1 replies)
[–] Not_mikey@slrpnk.net 8 points 2 weeks ago (1 children)

and Sudafed

Isn't Sudafed supposed to be short for pseudoephedrine , the stuff that actually works but they have to keep behind the counter?

[–] RandomGen1@lemm.ee 15 points 2 weeks ago

There's also Sudsfed PE which is Phenylephrine instead of pseudoephedrine. Presumably only the PE sub-brand would be banned under this rule

[–] BeMoreCareful@lemmy.world 8 points 2 weeks ago (6 children)

If you want some real solid advice: never buy the nasal spray that has phenylephrine. It may well be one of the most addictive substances man has ever made.

The pills do absolutely nothing. About once or twice a year I have to get the good stuff from the pharmacy, but I've refused to even buy the new stuff.

I can't help but feel like they could just put something in the regular Sudafed to make it not methy, but I took physics and not chemistry so idk.

load more comments (6 replies)
[–] NotMyOldRedditName@lemmy.world 5 points 2 weeks ago

I like in the article how it says they'll get some time to reformulate, but if it doesn't work, they could just turn off the widget inserting it and bobs your uncle!

[–] TherapyGary@lemmy.blahaj.zone 4 points 2 weeks ago (1 children)

Interesting. I use phenylephrine pills (no other active ingredients) for nasal congestion every time I'm sick, and it has always worked very well for me

I do tend to be extra sensitive to most drugs though, so maybe that has something to do with it

[–] Cethin@lemmy.zip 13 points 2 weeks ago

Maybe for you it does, although you'd need to test with placebo to really know. It's amazing how much our minds can effect things if we expect things to change.

It could also be that your pills are a significantly higher dose. If 1% is absorbed orally, maybe that pill has 100x the dose required otherwise.

load more comments
view more: next ›