RPGMemes

If you want some of that DnDness, I really liked 13th age, and Fanatsycarft. They are on opposite sides of the complexity spectrum. I liked those more than either PF. Ryutama taught me a lot of things about RPGs but a half assed combat system means I can't recommend it., especially for a longer campaign. However if you're interested in something on the experimental side, then I think its perfectly lovely for a one shot.

Daggerheart is new, and Im not particularly interested in CR, so I haven't really checked out Daggerheart beyond a cursory scan of the PDF.

I enjoyed the heck out of Icon. Exalted is also fun for your fantasy needs. Its a different flavor from dnd though, both mechanically and the kinds of stories they want you to tell. If you're looking for more flexible, open ended stories, fantasy or otherwise, I really liked Fate Accelerated.

Thats just if youre looking on the fantasy side of things. On the Sci fi side, Ive been playing Cyberpunk Red and really liking it (although fatigue has yet to set in.) I really liked Shadowrun 4e, and I recommend that to anyone who wants to dip into that (Karmagen optional rule and Chummer.exe are you best friends). Lancer is a heck of a thing.