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Tylenol.
Acetominaphen.
... Arguably the most common component of general, over the counter pain relievers... on the planet.
I mean...
https://jamanetwork.com/journals/jama/fullarticle/2817406
Here ya go, here's a 2024 study debunking the thing that RFK is likely referencing.
EDIT: Further, folinic acid as a 'treatment' for autism.
So... yes, there are early preliminary studies indicating that this may be a way of alliviating some of the effecfs of non-syndromic ASD.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5794882/
Non-syndromic ASD is essentially nonverbal, nonresponsive ASD.
... There are many autistic people and kids who are not non-syndromic, an ASD diagnosis does not even require this kind of behavior.
Further, the proposed mechanism of action in using folinic acid to 'treat' autism is that it acts upon an abnormal level of folate blockers...
While it is true that ASD folks tend to have more of these folate blockers than non ASD folks...
Many of them do not.
Generally speaking, abnormal folate pathways... appear to be called Cerebral Folate Disorder (CFD) by this Dr. Frye who seems to be spearheading this line of research.
... I am also somewhat concerned that many of his studies are funded by Autism Speaks, an organization notorious for, amongst other things, not actually allowing autistic people to speak, generally viewing autism, as Dr. Frye put it, 'a devastating life long condition', akin to leukemia (cancer of the blood) which must be cured, thus propogating a stigma, stereotype and fear of autism, and of course, being a shitty non-profit that spends the vast majority of its funding on 'operational costs', as opposed to... you know, actually doing things that might be helpful to autistic people... and more or less advocating eugenics while saying they aren't but then immediately afterwaed advocating a different kind of eugenics.
https://www.themarysue.com/the-autism-speaks-controversy-explained/
Nevertheless:
https://pubmed.ncbi.nlm.nih.gov/40362912/
There are a number of small scale studies like this one, done by people not directly associated with Dr. Frye, that do seem to show improvements amongst non syndromic ASD individuals who also have this folate abnormality and/or the genetic mutations that are associated with it....
But I am so far unable to find any large scale studies.
Soooooo...
Yeah.
I am going with 'very preliminary positive results for a subset of autistic people' on this one.
Maybe, maybe, at best, Dr. Frye has discovered an actually physically distinguishable subtype or subcomponent of ASD, and a potentially effective treatment for that subcomponent.
Maybe.
Oooorrrrr...
Maybe there should be a study which takes into account how ASD kids respond to folinic acid, when you also devise a way to measure whether or not the parents treat those.studied autistic kids as hopeless defectives, vs actual tiny people whose brains just work a bit differently.
There is still a huge amount of research showing that the 'nurture' component of a person's upbrining greatly affects their liklihood of developing, and severity of ASD.