this post was submitted on 30 Mar 2025
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My favorite is Barry Marshall. He thought there was a connection between bacteria and ulcers, which was an unpopular opinion at the time. So he intentionally drank the offending bacteria, got sick as expected, and then people believed him.
More here, including (which I didn't know until now) cardiac catheterization.
I'm sure better sources exist but https://www.discovermagazine.com/health/these-five-doctors-experimented-on-themselves-and-made-big-breakthroughs
If we allow animal experimentation it's only fair to also allow human experimentation
Only on consenting adults who have the ability to reasonably reject the offer (so they're not forced into it for any reason, like money). The guy in the picture did it on babies, so… if you want to do it on yourself go ham, but that wouldn't be fair. Animal experimentation is bad enough.