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Except we don't have any widespread evidence for cocaine being taken outside of highly specific medicinal cases being helpful to the health and wellbeing of the individual.
When it comes to gender affirming care, we have substantial evidence that proves it is safe and effective, as even a cursory glance at medical research on the topic will show:
https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(23)00118-7/fulltext
https://www.tandfonline.com/doi/full/10.3109/09540261.2015.1115753
https://jamanetwork.com/journals/jamanetworkopen/article-abstract/2789423
https://www.liebertpub.com/doi/full/10.1089/trgh.2015.0008
I still don’t disagree with anything you said