pterencephalon

I’m looking to re-purpose an old desktop into a multi-purpose home server. I’m looking for some advise on how to set things up in a way that won’t bite me in the ass later. I’m a confident Linux user, but have limited docker experience. I’m looking at using TrueNAS scale for: straight cloud storage, syncthings, home assistant, and tailscale to access it. If things go swimmingly, I might add jellyfin or *arr apps.

Here’s the hardware I already have:

• i7 6700
• 32 GB DDR4 (non-ECC)
• GTX 1060
• Storage:
  • 1 TB NVME SSD
  • 250 GB SATA SSD
  • 4x 4 TB WD Black HDD

So, here are my noob questions:

• Is this system capable enough to handle the things I want to do?
• My first pass at research says I should use TrueCharts for Tailscale. For Home Assistant, should I also install through TrueCharts? I was reading that you can’t install community docker plugins for home assistant, but I’m not sure if that’s something I’ll need. I also don’t know if I that’s something I need. The alternative is a separate VM, but that seems a lot more complicated.
• How should I set up my drives? Should the 1 TB NVME drive be the boot drive, is that better used for something else. I’ve done some basic reading on vdevs/pools, but I’m not sure how syncthings/home assistant/other apps fit into the picture. Any good resources you could point me to for understanding this better?