You need to pay attention to which Proton version is being engaged at what time for what specific game.
If you're pegged to the rolling release, it may break. That's why they keep the backlog of older versions available. One game may work perfectly on Proton9.0, but break on Proton10.0 release.
Check protondb.com and see if others are seeing the same thing, then go and change your compatible Proton versions in the game properties to peg it o a known good version.