Is there even such a thing as a "dose" for something that isn't a medication? She got sick eating way too much of a curry ingredient lol. I imagine people have had similar experiences with ghost peppers.
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My chemistry phd friend often says "The poison is in the dosage". For example you can overdose on water or other necessary substances.
Yep, water intoxication is indeed a thing. I first learned about it in a story about a clinic in England that had to install chemical toilets in a facility for treating people with water intoxication addiction issues.
Ahh my old science teacher (from Iowa, living in Australia) had a newspaper article from when he was attending university. A student had passed away after drinking I can't remember how many water shots, one including a goldfish. Decent teaching method in my eyes bringing real life consequences to stupid actions.
The same teacher, post exams would bring in a huge bag of popcorn and show us slides from his personal life. Was pressy interesting seeing snippets of his life. Up until we got a full crowning shot of his wife with their firstborn.
School was strange.
Oat bran: The Silent Killer
I suspect an oat bran OD would far from silent. :)
It looks like there are a few papers linking curcumin (a compound in turmeric) and black pepper to some health benefits relating to neurological diseases like alzheimers, but I don't think anything's been definitively proven yet.
https://www.sciencedirect.com/science/article/abs/pii/S0944711318302022
daily megadoses [...] Mohan was taking more than 10 times that
that's a decadose at best
Also microdoses are usually decidoses, but that's irrelevant because in this use mega means large and micro means small. Microcar. Microcomputer.
But what size are microplastics when also mentioning nanoplastics? Are they still "5mm and smaller"?
all very valid questions! also kilograms but never mega- or gigagrams?
Stop following Dr Oz, he's a quack!
I have to have taken that dose in the form of curry before
Oh yeah, it's basically a big teaspoon. Which isn't uncommon in a recipe of turmeric curry for two.
The issue here is that she took it straight in capsule form, every day, for several weeks.
Can't wait for the chubbyemu video to explain the science of what happens here
He's probably in the emergency room now, writing down all that is happening. "Hyperturmeremia - hyper- for high, turmer for turmeric, and -emia for presence in blood."
Commenters making blanket statements about quackery, and the dangers of the unregulated supplement industry - okay, yes, those are issues. But in this context, c'mon, Pubmed is right there. Turmeric is effective for exactly the things this social media doctor claimed it is, and a little more at that. I take half a teaspoon of the powder in my morning tea, and along with other lifestyle interventions I made a handful of years ago, the fairly significant chronic joint pain I used to experience has been a thing of the past.
This is an overdose story, nothing more.
https://pubmed.ncbi.nlm.nih.gov/30970601/
"The current study aimed to provide a comprehensive bibliometric overview of the literature on curcumin, complementing the previous reviews and meta-analyses on its potential health benefits. (...) The literature mainly focused on curcumin's effects against cancer, inflammation, and oxidative stress. Cancer types most frequently investigated were breast, colon, colorectal, pancreatic, and prostate cancers."
https://pubmed.ncbi.nlm.nih.gov/32075287/
"The use of curcumin reduces the subjective perception of the intensity of muscle pain; reduces muscle damage through the decrease of creatine kinase (CK); increases muscle performance; has an anti-inflammatory effect by modulating the pro-inflammatory cytokines, such as TNF-Ξ±, IL-6, and IL-8; and may have a slight antioxidant effect. In summary, the administration of curcumin at a dose between 150-1500 mg/day before and during exercise, and up until 72 h' post-exercise, improved performance by reducing EIMD and modulating the inflammation caused by physical activity. In addition, humans appear to be able to tolerate high doses of curcumin without significant side-effects."
Not so sure about the above line though, lol.
https://pubmed.ncbi.nlm.nih.gov/36898635/
"Curcumin supplementation significantly reduces anthropometric indices, and bioavailability-enhanced formulas are preferred. Augmenting curcumin supplement with lifestyle modification should be an option for weight reduction."
https://pubmed.ncbi.nlm.nih.gov/35979355/
"Curcumin and Curcuma longa Extract had good clinical efficacy in the treatment of Psoriasis, UC and RA, so Curcumin and Curcuma longa Extract could be used in the treatment of the above diseases in the future. The results of Meta-analysis showed that Curcumin and Curcuma longa Extract did not show efficacy in the treatment of oral lichen planus, while Takayasu arteritis, SLE, MS, AS, BD and CD did not report sufficient clinical data for meta-analysis. Therefore, large-sample, multi-center clinical trials are still needed for revision or validation."
https://pubmed.ncbi.nlm.nih.gov/36804260/
"We observed that turmeric/curcumin supplementation significantly reduces levels of inflammatory markers (...) Also, turmeric/curcumin supplementation significantly improved anti-oxidant activity (...) It seems that turmeric/curcumin supplementation might be used as a viable intervention for improving inflammatory/oxidative status of individuals."
https://pubmed.ncbi.nlm.nih.gov/37325651/
"Curcumin is beneficial for rheumatoid arthritis treatment. Inflammation levels and clinical symptoms in patients with rheumatoid arthritis can be improved by curcumin supplementation. Large sample randomized controlled trials on the effects of curcumin on patients with rheumatoid arthritis are needed in the future."
https://pubmed.ncbi.nlm.nih.gov/34012421/
"The results showed that curcumin's anti-diabetic activity might be due to its capacity to suppress oxidative stress and inflammatory process. Also, it significantly reduces fasting blood glucose, glycated hemoglobin, and body mass index. Nanocurcumin is also associated with a significant reduction in triglycerides, VLDL-c, total cholesterol, LDL-c, HDL-c, serum C reactive protein, and plasma malonaldehyde. Therefore, it can be considered in the therapeutic approach of patients with DM."
In my bathroom cabinet I have 6250mg tumeric gummies, which I take in the morning with my multivitamin for inflammation. I bought this well known brand (Jamieson) from a reputable source.
Am I not supposed to be able to trust that a basic suppliment from Shoppers is safe? This isn't "magic sleep improvement concoction" or some underground fad wellness brand selling mushroom infusions.... This is a large and old company that makes half the shit in my cabinet....
googling for 3 seconds I found that Jamieson Tumeric Gummies only have 250mg Tumeric per Gummy, which is apparently equivalent to 6250mg of dried Tumeric. That is basically the recommended maximum daily dosage.
In general, no you can't trust 'basic' supplements, since they are poorly regulated. I'd also recommend getting supplements only for things that you actually need supplemented, i.e. a blood test shows you are deficient.
https://www.npr.org/transcripts/1143270524?ft=nprml&%3Bf=1143270524
Thank you for doing that. I found this out first thing in the morning and am now on my first work break, I hope I would have figured this out eventually but it was bothering me already today. My workmate had the rational thought "it's got to be a factor of 10 difference or something, you should reread the label when you get home."
But again, thanks, now I have a little peace in my head until I can do some more research. I poison my liver with alcohol. I don't need extra help....
As for why I take it, I was instructed to by my family doctor as well as my (far more trusted and who I've known far longer) Massage therapist, who explicitly said "I can't legally tell you to take supplements because laws and such, but go ask your doctor about x,y,z." Which I did.
Massage therapists aren't licensed. Do not take medical advice from them. They know exactly as much about medicine as your plumber.
Massage therapists are fully licenced where I live (Canada) They are not, however, licenced to give advice about supplements. Which is why she told me to go to my doctor. But since she went to school for years and takes annual courses to keep up to date on human bodies and how they function, and she spends every day of her life literally hands on hundreds of different human bodies for the past 25 years so far, I'd say she has a much better grasp on how supplements affect people than my plumber, if I had a plumber.
So you're saying I shouldn't take one of those supplements then go have a curry?
NO, you cannot, because they are NOT regulated in any way. 'Supplements' are not FDA approved. They are not tested to ensure safety. They basically do whatever they want until someone else proves it's unsafe.
You should read the article in full, and keep an eye on the listed symptoms. Your dose does sound pretty high, but it also sounds like some people conditionally react to turmeric worse than others do.
I've read elsewhere that turmeric also reduces the absorption of some minerals. So I have it with my tea, as opposed to in my food.
As a random internet person who knows not much about anything, you should definitely take them.