I have been using a pair of Roth Audio OLi-RA1 speakers with my computer, they are real stereo speakers and require an amplifier to wire them up and power them.
The are excellent speakers, good general speakers, and not that expensive.
I don't use a subwoofer, but it isn't really needed for me, I do miss some sub bass, but that never bothered me.
I am currently running them with a no brand Chinese analog amp, from the soubd out on my monitor that is connected to my computer with DisplayPort.
Works great.
I sm considering getting a Dennon RCD-M41 tl replace my amp, but have not had any need to do so in the last eight years.