Anthopology has provided clear evidence, in all times, in all tribes and continents, the percentage of people that will abuse substances that affect the mind has been steady, and there is nothing anyone can do about it, they will find the substance in the wilderness if it is not in the market.

Alternatively both politically and economically certain entities will use this weakness to control and manipulate people, either by promoting one, or by criminalizing another. Miami became big and important during prohibition because politicians would travel down there to drink and ... whatever else they needed. Bootlegging lasted twice or more after prohibition was reverted, mostly because industrial production wasn't there to cover the need/market.

Opium smoking was common in Europe among the elites all the way to early 20th century. The poor just smoked cheaper stuff.

The WHO are hypocrites than need to hang high and dry